Pharmaceutical companies work throughout their supply chain in a field dominated by regulations and demands for high quality. Anton Paar offers a comprehensive product portfolio for R&D, production and quality control.
MCP polarimeters measure the optical rotation of substances. They are the ideal instruments for quick incoming checks on raw materials, reliably identifying correct substances during production and in the final product as part of quality control.
The Propol online polarimeter enables real-time monitoring of the correct production and formation of an active ingredient in the correct chirality.
Refractive index quickly determined
Refractometers measure the refractive index, which correlates to the concentration of a dissolved substance. For quality control laboratories in particular, it is important to have reproducible results available simply and quickly for the approval of batches or correction of ongoing production.
Density measurement for quality control
Density measurement provides insight into the condition of pharmaceutical raw materials as well as into the finished medicine. Based on the results, it is possible to intervene quickly and ensure that the production and the final product are within the defined specifications.
"Density measurement provides insight into the condition of pharmaceutical raw materials and the finished medicine."
An added plus is the combination of density and sound velocity measurement in one instrument, which delivers highly precise and reproducible results for complex three-component solutions. Density measurement is based on the oscillating U-tube principle and corresponds to the requirements of pharmacopoeia such as USP, Ph.Eur, JP and MX.
Determining the viscosity of liquids
The Lovis 2000 M viscometer determines the dynamic, kinematic, relative and intrinsic viscosity of liquids. It is ideal for quality control checks on valuable active agents because it requires a low sample volume of only 0.1ml.
Synthesis
Using microwave synthesis reduces costs for chemicals and synthesis time compared with using conventional organic synthesis. The selected synthesis steps in the small scale can also be optimised during the development process in the multimode reactor.
"The Lovis 2000 M viscometer is ideal for quality control checks on valuable active agents."
Transfer of suitable reaction parameters from the small scale to the kilolab scale is now possible with the monomode reactor without adjusting the methods and technology.
Microwave-assisted synthesis with the monomode reactor is particularly suitable for the manufacture of expensive and difficult to access pharmaceutical agents in small amounts.
Investigating the flow behaviour
The measurement of liquids to investigate their viscous and viscoelastic behaviour is important in order to determine the flow properties of formulations under controlled conditions and to optimise formulations to ensure that products have the required properties.
The MCR rheometers are ideal for defining the flow properties, process parameters and stabilities of the products.
